Precision, anywhere.
High-accuracy molecular diagnostics, designed for real-world use.
LUNAS
Molecular diagnostics at the point-of-care.
LUNAS (Luminescent Nucleic Acid Sensor) is a CRISPR-based molecular diagnostic platform that enables rapid, highly sensitive detection of pathogens without the need for centralized laboratory infrastructure. It integrates isothermal amplification, CRISPR-based detection, and a luminescent camera-based readout into a single highly sensitive and specific reaction.
For more detailed information on the underlying science, see:
Glow-in-the-Dark Infectious Disease Diagnostics Using CRISPR-Cas9-Based Split Luciferase Complementation. van der Veer HJ, van Aalen EA, Michielsen CMS, Hanckmann ETL, Deckers J, van Borren MMGJ, Flipse J, Loonen AJM, Schoeber JPH, and Merkx M. ACS Cent Sci. 2023 doi: 10.1021/acscentsci.2c01467. Epub 2023 Mar 15.
Multicolor Bioluminescent Toolbox for Multiplex Glow-in-the-Dark Nucleic Acid Diagnostics. de Stigter Y, van der Veer HJ, Couwenberg JLJ, Kolen IHM, Schlaghecke JM, Migneaux J, Treure BAA, Gionkar BRL, Bossink MMB, Versluijs H, Wolffs PFG, Loonen AJM, Schoeber JPH, Merkx M. ACS Sens. 2026 Apr 23. doi: 10.1021/acssensors.5c05012.
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